Volume 2, Issue 2

In Vitro Antimicrobial Activity of Alangium salviifoliium L. Roots.

Author

Krishna Rao M1*, Aniel Kumar O2 and L. Mutyala Naidu2

Abstract

The antimicrobial activity of the roots of Alangium salviifoliium L. studied
against bacteria, Bacillus subtilis, Escherichia coli, Klebsiella pneumoniae,
Pseudomonas aeruginosa, Proteus vulgaris, Staphylococcus aureus,
Streptomyces pneumoniae and fungi Aspergillus niger, Candida albicans
and Saccharomyces cerevisiae by the agar well diffusion method.
Antimicrobial activity was recorded in the order of hexane, chloroform,
methanol, ethanol and water extracts. Three concentrations (50, 75 and 100
mg/ml) of each extracts were studied in the antimicrobial activity which
involved the determination of inhibition zone values. As the extract dosage
level increases the inhibitory effect also increased. All the extracts have
showed antimicrobial activity against all tested bacteria and fungi. Ethanol
extract has exhibited the highest antimicrobial activity against Proteus
vulgaris followed by Candida albicans and Saccharomyces cerevisiae,
while methanol extract exhibited the highest activity against Streptomycis
pneumoniae. The antimicrobial activity of the extracts was compared to the
standard antibiotics, Tetracycline and Clotrimazole. The minimum
inhibitory concentration of the chloroform, methanol, ethanol and water
extracts were determined by the agar dilution method ranged between 10-
1000 μg/ml and 10 μg/ml with that of Proteus vulgaris being the least
phytochemical screening of the plant revealed the presence of tannins,
alkaloids, flavonoids and saponins. The results of this study support the
traditional use of Alangium salviifoliium L. root as an antimicrobial agent.

DOI

https://doi.org/10.62226/ijarst20130264

PAGES : 88-91 | 32 VIEWS | 78 DOWNLOADS

Download Full Article