Volume 13, Issue 6

Mixed Ligand Complexes: Room Temperature Synthesis, Structure Determination and Biological Utility

Author

Vikas D. Ragole

Abstract

The synthesis of mixed ligand complexes at room temperature involving a Schiff base derived from a heterocyclic compound (S5) and 5-chloro-8-hydroxyquinoline ligands, utilizing transition metals such as Fe(III), Co(II), Ni(II), and Cu(II), has been documented. The formation of the Schiff base (S5) is achieved by reacting 2-hydroxy-3-methoxy-5-nitrobenzaldehyde with 2-aminobenzothiazole in ethanol, with glacial acetic acid serving as a catalyst. Various analysis techniques utilized to analyze the obtained compounds for their structure determination. Biological screening results revealed the obtained metal-ligand combinations are possible candidates for use as antibacterial, antimalarial and antioxidant agents owing to their potential activities.

DOI

https://doi.org/10.62226/ijarst202413190

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