Volume 13, Issue 7

"Hydrotropy: A Promising Technique for Solubility Enhancement in Drug Delivery"

Author

1Ms. Sanskruti K. Wagh, 2Mr. Nilesh Salunke ,3Prof. Sayyad J.H., 4Prof. Akolkar P.B., 5Mr Rahul Jadhav.

Abstract

In both formulation research and screening studies of novel chemical entities, solubilization of poorly water-soluble pharmaceuticals has shown to be a crucial problem. Hydrotropic solubilization is a technique employed to enhance the water solubility of pharmaceuticals with poor aqueous solubility. Something that solubilizes hydrophobic substances in water solution is called a hydrotrope. The issue with emulsification, which is typically. Hydrotrope solutions do not include the contaminants found in traditional surfactant solutions. This approach is the most efficient, especially at industrial levels, because it is simple to recover the dissolved solute and because hydrotrope solutions can be reused. Moreover, this method is favored over others because it offers certain benefits such as pH-independent solvent properties, high selectivity, non-flammability, and the affordability and ease of access to hydrotropes.

DOI

https://doi.org/10.62226/ijarst20241377

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